MR Imaging Biomarkers


Neurosurgery Quantitative MR imaging, Biopsy planning, Pre-Surgery planning, Post-therapeutic Monitoring

Image-guided surgery is rapidly developing into an essential tool for neurosurgeons. KIO group uses optimized images for accurate guidance of surgical operations, quantification of advanced MR images, and integration of MRI-derived biomarkers using artificial intelligence (AI) methods for accurate localization and delineation of lesion borders used for planning surgical procedures.

Our Diagnostic and Treatment Services in Neurosurgery include advanced Quantitative MRI analysis:

  • Perfusion Imaging using ASL (Perfusion Cerebral Analysis without Contrast Agent Injection) or using Contrast-based perfusion imaging (DSC- or DCE-MRI)
  • Functional MR imaging (fMRI): Determination of the brain function during a given task
  • Diffusion tensor imaging (DTI): Evaluating the microstructural alterations of the fiber /analysis of nerve fibers and generating RD, MD, FA and AD maps
  • Susceptibility Weighted Imaging (SWI): Identification of both hemorrhagic and calcified foci in the brain
  • Volumetric MRI: Measuring different regional brain atrophy and cortical thickness cortex thickness
  • DWI: Analysis of tissue cell density
  • Radiomic analysis: Characterizing lesion heterogeneity, shape, volume, etc.

Specific Application:

  • Intracranial neoplasms
  • Gliomas
  • Metastases
  • Primary cerebral lymphomas
  • Tumor-mimicking lesions
  • Tumefactive demyelinating lesions
  • follow-up Recovery after surgery
  • Spine disorders
Neurology Quantitative MR imaging


  • Enhancement computation
  • Wash-out computation
  • ADC computation
  • Tractography
  • Activation Map


  • Volume and measures
  • Enhancement histogram
  • Kinetics repartition


  • Standardized reports
  • Easy data sharing


  • Texture Analysis
  • IVIM computation
  • DCE computation
  • Kurtosis computation
  • MRS